BDBM50130286 5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide::CHEMBL29846::SB-258510

SMILES COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCN(C)CC1

InChI Key InChIKey=ZINLARKOVIPOJW-UHFFFAOYSA-N

Data  18 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50130286   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130286(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130286(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  0.631nMAssay Description:The compound was tested for the binding affinity towards human cloned 5-hydroxytryptamine 6 receptor in HeLa cells, using [3H]5-LSD as radioligand; n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50130286(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  0.760nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(MOUSE)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50130286(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130286(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  1.02nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed